Umbria Umbria is located in the center of Italy, in the Apennines north of Rome and east of Toscana. Its capital and largest city is Perugia. Tourists love Umbria for its medieval hill towns such as Assisi and Spoleto. In the wine world, Umbria is best known for white wines from one of those hill towns, Orvieto, and red wines from another, Montefalco. The region has 2 DOCGs, 13 DOCs (see map), and 6 IGPs. In 2016, Umbria produced 815,000 hl (9 million cases) of wine. The region’s primary grape varieties are Sangiovese (22%), Trebbiano (17%), and Grechetto (13%).